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Comfortis Chewable Tablets  are a meat flavoured tablet that rapidly kills adult fleas on dogs and cats, then goes on to prevent flea infestations for a further month.  Comfortis starts to kill fleas within 30 minutes of administration and will kill 100%  of fleas on a dog within 4 hours, and 90% of fleas on a cat within 2 hours and 100% within 24 hours.

The chewable meat flavoured tablet is readily accepted by dogs and cats, and as the product is an oral medication there are no restrictions with regards to swimming or washing after treatment.
 
Manufacturer
Elanco

Active Ingredient
Spinosad

Directions of Use
Comfortis tablets are administered orally once a month at the recommended minimum dosage of 30 mg/kg. Comfortis should be given with food. 

Comfortis is recommended for use in dogs and cats 14 weeks of age or older. Comfortis tablets are given orally, once a month at the recommended minimum dosage of 30 mg/kg body weight for dogs, and 50 mg/kg body weight for cats, as specified in the following table:

Recommended Dosage Schedule:

*Cats over 11.2 kg should be administered the appropriate combination of tablets.

In both dogs and cats, spinosad is rapidly absorbed and extensively distributed after oral administration. Because of the longer half-life in cats compared with dogs, the dosing interval must not be decreased to less than monthly in cats.

Caution
Keep out of reach of children. Give this medication with food. Comfortis should not be administered to puppies or kittens less than 14 weeks of age. Seek veterinary advice regarding use of Comfortis in pregnant and lactating female dogs and in animals with pre-existing epilepsy.

The safe use of Comfortis in breeding male dogs has not been evaluated. The safe use of Comfortis in breeding, pregnant, lactating female cats or breeding male cats has not been evaluated.

Comfortis may be safely administered to dogs in conjunction with topical tick treatments and collars as well as heartworm and worming medications when used according to label directions.

In cats, the safety of Comfortis in conjunction with macrocyclic lactone-containing gastrointestinal worm treatments or heartworm preventatives and with topical tick treatments and collars has not been evaluated.

Possible Side Effects
Side effects of Comfortis are rare in dogs and are considered mild. The most common side effect in dogs is vomiting followed by decreased appetite lethargy and diarrhoea. Reactions are usually short lived and decrease with repeated dosing.